What Is Your Guess?

what is your diagnosis?

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What is your guess? Lactescent plasma in acute leukemia.

A 15-year-old white girl presented with headaches and night sweats of 2 weeks’ duration. Her platelet count was 50 10/ L (50 10/L) [reference interval, 140–440 10/ L (140–440 10/L)]. Upon referral to hematology/oncology, the patient had a leukocyte count of 21 10/ L (21 10/L) [reference interval, 3.8–9.8 10/ L (3.8–9.8 10/L)] with 46% lymphoblasts. The patient was diagnosed with pre-B acute lym...

what is your diagnosis?

What is your guess? A four-day-old boy with an abnormal metabolic screen.

A four-day-old boy with a positive result in newborn-screening testing was referred to the hospital for further evaluation. He was the product of a 39-week gestation and appeared well at birth. His laboratory results included the following plasma findings: ammonia, 109 g/dL (reference interval, 20 – 65 g/dL); citrulline, 169 mol/L (reference interval, 2–50 mol/L); and leucine, 278 mol/L (refere...

What is your guess? A 42-year-old woman with fever after a trip to Africa.

A 42-year-old woman was admitted with fever. Two weeks prior, she had returned from a 1-month stay in the Comoros archipelago (islands situated to the east of Mozambique), during which she had not taken antimalarial prophylaxis. Her medical history included a total splenectomy during surgery for a gastrointestinal stromal tumor 2 years before. A thin smear of blood revealed the findings seen in...